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Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma
Antibodies against CD47, which block tumor cell CD47 interactions with macrophage signal regulatory protein-α, have been shown to decrease tumor size in hematological and epithelial tumor models by interfering with the protection from phagocytosis by macrophages that intact CD47 bestows upon tumor c...
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| Asıl Yazarlar: | , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340056/ https://ncbi.nlm.nih.gov/pubmed/22451919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121629109 |
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