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Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma
Antibodies against CD47, which block tumor cell CD47 interactions with macrophage signal regulatory protein-α, have been shown to decrease tumor size in hematological and epithelial tumor models by interfering with the protection from phagocytosis by macrophages that intact CD47 bestows upon tumor c...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
National Academy of Sciences
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340056/ https://ncbi.nlm.nih.gov/pubmed/22451919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121629109 |
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