Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma

Antibodies against CD47, which block tumor cell CD47 interactions with macrophage signal regulatory protein-α, have been shown to decrease tumor size in hematological and epithelial tumor models by interfering with the protection from phagocytosis by macrophages that intact CD47 bestows upon tumor c...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Edris, Badreddin, Weiskopf, Kipp, Volkmer, Anne K., Volkmer, Jens-Peter, Willingham, Stephen B., Contreras-Trujillo, Humberto, Liu, Jie, Majeti, Ravindra, West, Robert B., Fletcher, Jonathan A., Beck, Andrew H., Weissman, Irving L., van de Rijn, Matt
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2012
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340056/
https://ncbi.nlm.nih.gov/pubmed/22451919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121629109
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