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Antiseizure Effects of TrkB Kinase Inhibition

OBJECTIVE: The principal molecular targets of conventional antiseizure drugs consist of ligand-and voltage-gated ion channels and proteins subserving synaptic function. Inhibition of the receptor tyrosine kinase TrkB limits epileptogenesis, but its effect on individual seizures is unknown. We sought...

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Main Authors: Liu, Gumei, Kotloski, Robert J, McNamara, James O
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126863/
https://ncbi.nlm.nih.gov/pubmed/24903749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.12671
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