Transient Inhibition of TrkB Kinase Following Status Epilepticus Prevents Development of Temporal Lobe Epilepsy

Temporal lobe epilepsy is the most common and often devastating form of human epilepsy. The molecular mechanism underlying the development of temporal lobe epilepsy remains largely unknown. Emerging evidence suggests that activation of the BDNF receptor, TrkB, promotes epileptogenesis caused by stat...

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Main Authors: Liu, Gumei, Gu, Bin, He, Xiao-Ping, Joshi, Rasesh B., Wackerle, Harold D., Rodriguiz, Ramona Marie, Wetsel, William C., McNamara, James O.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744583/
https://ncbi.nlm.nih.gov/pubmed/23790754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.04.027
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