Transient Inhibition of TrkB Kinase Following Status Epilepticus Prevents Development of Temporal Lobe Epilepsy

Temporal lobe epilepsy is the most common and often devastating form of human epilepsy. The molecular mechanism underlying the development of temporal lobe epilepsy remains largely unknown. Emerging evidence suggests that activation of the BDNF receptor, TrkB, promotes epileptogenesis caused by stat...

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Autori principali: Liu, Gumei, Gu, Bin, He, Xiao-Ping, Joshi, Rasesh B., Wackerle, Harold D., Rodriguiz, Ramona Marie, Wetsel, William C., McNamara, James O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744583/
https://ncbi.nlm.nih.gov/pubmed/23790754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.04.027
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