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Reduction of TrkB Expression De Novo in the Adult Mouse Impairs Epileptogenesis in the Kindling Model

Elucidating the mechanisms of epileptogenesis in molecular terms can identify targets for therapies aimed at preventing epileptogenesis or limiting its progression. Genetic perturbations have implicated signaling by the neurotrophin, BDNF, and its receptor, TrkB, in limbic epileptogenesis. Whether t...

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Bibliografiske detaljer
Main Authors: Kotloski, Robert, McNamara, James O.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381502/
https://ncbi.nlm.nih.gov/pubmed/19603519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hipo.20673
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