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Reduction of TrkB Expression De Novo in the Adult Mouse Impairs Epileptogenesis in the Kindling Model

Elucidating the mechanisms of epileptogenesis in molecular terms can identify targets for therapies aimed at preventing epileptogenesis or limiting its progression. Genetic perturbations have implicated signaling by the neurotrophin, BDNF, and its receptor, TrkB, in limbic epileptogenesis. Whether t...

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Bibliografske podrobnosti
Main Authors: Kotloski, Robert, McNamara, James O.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381502/
https://ncbi.nlm.nih.gov/pubmed/19603519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hipo.20673
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