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Regression of epileptogenesis by inhibiting TrkB signaling following a seizure

OBJECTIVE: Temporal lobe epilepsy (TLE) is a devastating disease in which seizures persist in 35% of patients despite optimal use of antiseizure drugs. Clinical and preclinical evidence implicates seizures themselves as one factor promoting epilepsy progression. What is the molecular consequence of...

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Krishnamurthy, Kamesh, Huang, Yang Zhong, Harward, Stephen C., Sharma, Keshov K., Tamayo, Dylan L., McNamara, James O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7531259/
https://ncbi.nlm.nih.gov/pubmed/31525273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25602
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