Random and targeted transgene insertion in C. elegans using a modified Mosl transposon

We have generated a recombinant Mos1 transposon that can insert up to 45 kb transgenes into the C. elegans genome. The minimal Mos1 transposon (miniMos) is 550 bp long and inserts DNA into the genome at high frequency (~60% of injected animals). Genetic and antibiotic markers can be used for selecti...

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Autori principali: Frokjaer-Jensen, Christian, Davis, M Wayne, Sarov, Mihail, Taylor, Jon, Flibotte, Stephane, LaBella, Matthew, Pozniakovski, Andrei, Moerman, Donald G, Jorgensen, Erik M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126194/
https://ncbi.nlm.nih.gov/pubmed/24820376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2889
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