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Single copy insertion of transgenes in C. elegans
Currently transgenes in C. elegans are generated by injecting DNA into the germline. The DNA assembles into a semi-stable extrachromosomal array composed of many copies of injected DNA. These transgenes are typically overexpressed in somatic cells and silenced in the germline. We have developed a me...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749959/ https://ncbi.nlm.nih.gov/pubmed/18953339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.248 |
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