Myeloid zinc finger 1 mediates sulindac sulfide-induced upregulation of death receptor 5 of human colon cancer cells

A combined therapy of sulindac sulfide and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising strategy for the treatment of cancer. Sulindac sulfide had been shown to induce the expression of death receptor 5 (DR5), a receptor for TRAIL, and sensitize cancer cells to TRAI...

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Autores principales: Horinaka, Mano, Yoshida, Tatsushi, Tomosugi, Mitsuhiro, Yasuda, Shusuke, Sowa, Yoshihiro, Sakai, Toshiyuki
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126006/
https://ncbi.nlm.nih.gov/pubmed/25102912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06000
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