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Discovery of novel aromatase inhibitors using a homogeneous time-resolved fluorescence assay
AIM: Aromatase is an important target for drugs to treat hormone-dependent diseases, including breast cancer. The aim of this study was to develop a homogeneous time-resolved fluorescence (HTRF) aromatase assay suitable for high-throughput screening (HTS). METHODS: A 384-well aromatase HTRF assay wa...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4125720/ https://ncbi.nlm.nih.gov/pubmed/25047514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.53 |
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