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DNA ligase III and DNA ligase IV carry out genetically distinct forms of end joining in human somatic cells
Ku-dependent C-NHEJ (classic non-homologous end joining) is the primary DNA EJing (end joining) repair pathway in mammals. Recently, an additional EJing repair pathway (A-NHEJ; alternative-NHEJ) has been described. Currently, the mechanism of A-NHEJ is obscure although a dependency on LIGIII (DNA li...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4125535/ https://ncbi.nlm.nih.gov/pubmed/24837021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.04.015 |
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