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A mechanistic link between gene regulation and genome architecture in mammalian development

The organization of chromatin within the nucleus and the regulation of transcription are tightly linked. Recently, mechanisms underlying this relationship have been uncovered. By defining the organizational hierarchy of the genome, determining changes in chromatin organization associated with change...

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Autores principales: Bonora, Giancarlo, Plath, Kathrin, Denholtz, Matthew
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125518/
https://ncbi.nlm.nih.gov/pubmed/24998386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2014.05.002
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