(+)-2-(1-Hydroxyl-4-oxocyclohexyl) ethyl caffeate suppresses solar UV-induced skin carcinogenesis by targeting PI3-K, ERK1/2 and p38

For decades, skin cancer incidence has increased, mainly due to oncogenic signaling pathways activated by solar ultraviolet (UV) irradiation (i.e., sun exposure). Solar UV induces multiple signaling pathways that are critical in the development of skin cancer, and therefore the development of compou...

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Autores principales: Lim, Do Young, Lee, Mee-Hyun, Shin, Seung Ho, Chen, Hanyoung, Ryu, Joohyun, Shan, Lei, Li, Honglin, Bode, Ann M., Zhang, Wei-Dong, Dong, Zigang
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125463/
https://ncbi.nlm.nih.gov/pubmed/24845061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-13-0286
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