(+)-2-(1-Hydroxyl-4-oxocyclohexyl) ethyl caffeate suppresses solar UV-induced skin carcinogenesis by targeting PI3-K, ERK1/2 and p38

For decades, skin cancer incidence has increased, mainly due to oncogenic signaling pathways activated by solar ultraviolet (UV) irradiation (i.e., sun exposure). Solar UV induces multiple signaling pathways that are critical in the development of skin cancer, and therefore the development of compou...

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Detalhes bibliográficos
Main Authors: Lim, Do Young, Lee, Mee-Hyun, Shin, Seung Ho, Chen, Hanyoung, Ryu, Joohyun, Shan, Lei, Li, Honglin, Bode, Ann M., Zhang, Wei-Dong, Dong, Zigang
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125463/
https://ncbi.nlm.nih.gov/pubmed/24845061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-13-0286
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