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The characteristics of astrocyte on Aβ clearance altered in Alzheimer’s disease were reversed by anti-inflammatory agent (+)-2-(1-hydroxyl-4-oxocyclohexyl) ethyl caffeate

Astrocytes are closely related to the amyloid-β (Aβ) deposition in the brain and play crucial roles in Alzheimer’s disease (AD) pathology. Meanwhile, inflammation in the CNS has been increasingly demonstrated as a prominent hallmark in AD. Our data from animal models and subjects with Alzheimer’s di...

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Pubblicato in:Am J Transl Res
Autori principali: Liu, Rui-Xuan, Huang, Cui, Bennett, David A, Li, Honglin, Wang, Rui
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095303/
https://ncbi.nlm.nih.gov/pubmed/27829994
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