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(+)-2-(1-Hydroxyl-4-oxocyclohexyl) ethyl caffeate suppresses solar UV-induced skin carcinogenesis by targeting PI3-K, ERK1/2 and p38

For decades, skin cancer incidence has increased, mainly due to oncogenic signaling pathways activated by solar ultraviolet (UV) irradiation (i.e., sun exposure). Solar UV induces multiple signaling pathways that are critical in the development of skin cancer, and therefore the development of compou...

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Main Authors: Lim, Do Young, Lee, Mee-Hyun, Shin, Seung Ho, Chen, Hanyoung, Ryu, Joohyun, Shan, Lei, Li, Honglin, Bode, Ann M., Zhang, Wei-Dong, Dong, Zigang
格式: Artigo
語言:Inglês
出版: 2014
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125463/
https://ncbi.nlm.nih.gov/pubmed/24845061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-13-0286
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