miR-150 influences B-cell receptor signaling in chronic lymphocytic leukemia by regulating expression of GAB1 and FOXP1

We examined the microRNAs (miRNAs) expressed in chronic lymphocytic leukemia (CLL) and identified miR-150 as the most abundant, but with leukemia cell expression levels that varied among patients. CLL cells that expressed ζ-chain–associated protein of 70 kDa (ZAP-70) or that used unmutated immunoglo...

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Detalhes bibliográficos
Main Authors: Mraz, Marek, Chen, Liguang, Rassenti, Laura Z., Ghia, Emanuela M., Li, Hongying, Jepsen, Kristen, Smith, Erin N., Messer, Karen, Frazer, Kelly A., Kipps, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125356/
https://ncbi.nlm.nih.gov/pubmed/24787006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-09-527234
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