A molecular anchor for stabilizing triple-helical DNA.
Molecular modeling has been used to predict that 2,6-disubstituted amidoanthraquinones, and not the 1,4 series, should preferentially interact with and stabilize triple-stranded DNA structures over duplex DNA. This is due to marked differences in the nature of chromophore-base stacking and groove ac...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1995
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41251/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7644509/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.17.7887 |
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