A System for Genome-Wide Histone Variant Dynamics In ES Cells Reveals Dynamic MacroH2A2 Replacement at Promoters

Dynamic exchange of a subset of nucleosomes in vivo plays important roles in epigenetic inheritance of chromatin states, chromatin insulator function, chromosome folding, and the maintenance of the pluripotent state of embryonic stem cells. Here, we extend a pulse-chase strategy for carrying out gen...

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Bibliographic Details
Main Authors: Yildirim, Ozlem, Hung, Jui-Hung, Cedeno, Ryan J., Weng, Zhiping, Lengner, Christopher J., Rando, Oliver J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125097/
https://ncbi.nlm.nih.gov/pubmed/25102063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004515
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