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Tethering Sister Centromeres to Each Other Suggests the Spindle Checkpoint Detects Stretch within the Kinetochore

The spindle checkpoint ensures that newly born cells receive one copy of each chromosome by preventing chromosomes from segregating until they are all correctly attached to the spindle. The checkpoint monitors tension to distinguish between correctly aligned chromosomes and those with both sisters a...

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Bibliographic Details
Main Authors: Nannas, Natalie J., Murray, Andrew W.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125069/
https://ncbi.nlm.nih.gov/pubmed/25101645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004492
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