Flap endonuclease of bacteriophage T7: Possible roles in RNA primer removal, recombination and host DNA breakdown

Gene 6 protein of bacteriophage T7 has 5′-3′-exonuclease activity specific for duplex DNA. We have found that gene 6 protein also has flap endonuclease activity. The flap endonuclease activity is considerably weaker than the exonuclease activity. Unlike the human homolog of gene 6 protein, the flap...

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Bibliographic Details
Main Authors: Mitsunobu, Hitoshi, Zhu, Bin, Lee, Seung-Joo, Tabor, Stanley, Richardson, Charles C
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124056/
https://ncbi.nlm.nih.gov/pubmed/25105057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bact.28507
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