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Entropy-enthalpy compensation: Role and ramifications in biomolecular ligand recognition and design
Recent calorimetric studies of small molecule interactions with biomolecular targets have generated renewed interest in the phenomenon of entropy-enthalpy compensation. In these studies, entropic and enthalpic contributions to binding are observed to vary substantially and in an opposing manner as t...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4124006/ https://ncbi.nlm.nih.gov/pubmed/23654303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biophys-083012-130318 |
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