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Extent of enthalpy–entropy compensation in protein–ligand interactions

The extent of enthalpy–entropy compensation in protein–ligand interactions has long been disputed because negatively correlated enthalpy (ΔH) and entropy (TΔS) changes can arise from constraints imposed by experimental and analytical procedures as well as through a physical compensation mechanism. T...

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Detalhes bibliográficos
Main Authors: Olsson, Tjelvar S G, Ladbury, John E, Pitt, Will R, Williams, Mark A
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190155/
https://ncbi.nlm.nih.gov/pubmed/21739503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.692
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