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Targeting Breast Tumors with pH (Low) Insertion Peptides

[Image: see text] Extracellular acidity is associated with tumor progression. Elevated glycolysis and acidosis promote the appearance of aggressive malignant cells with enhanced multidrug resistance. Thus, targeting of tumor acidity can open new avenues in diagnosis and treatment of aggressive tumor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Adochite, Ramona-Cosmina, Moshnikova, Anna, Carlin, Sean D., Guerrieri, Renato A., Andreev, Oleg A., Lewis, Jason S., Reshetnyak, Yana K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123937/
https://ncbi.nlm.nih.gov/pubmed/25004202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp5002526
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