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Construction and Application of a Rh–Pt DNA Metalloinsertor Conjugate

[Image: see text] We report the synthesis and characterization of a bimetallic conjugate (RhPt) in which an oxaliplatin derivative is tethered to a rhodium metalloinsertor through an aminomalonate leaving group ligand. The complex interacts with DNA through metalloinsertion at a base pair mismatch f...

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Bibliografiske detaljer
Main Authors: Weidmann, Alyson G., Barton, Jacqueline K.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123934/
https://ncbi.nlm.nih.gov/pubmed/25032512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ic501509x
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