Decreased Interleukin-20 Expression in Scleroderma Skin Contributes to Cutaneous Fibrosis

OBJECTIVE: To clarify the role of interleukin-20 (IL-20) in the regulatory mechanism of extracellular matrix expression and to determine the contribution of IL-20 to the phenotype of systemic sclerosis (SSc). METHODS: Protein and messenger RNA (mRNA) levels of collagen, Fli-1, IL-20, and IL-20 recep...

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Autors principals: Kudo, Hideo, Jinnin, Masatoshi, Asano, Yoshihide, Trojanowska, Maria, Nakayama, Wakana, Inoue, Kuniko, Honda, Noritoshi, Kajihara, Ikko, Makino, Katsunari, Fukushima, Satoshi, Ihn, Hironobu
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123870/
https://ncbi.nlm.nih.gov/pubmed/24470401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38380
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