Knockout of Endothelial Cell-Derived Endothelin-1 Attenuates Skin Fibrosis but Accelerates Cutaneous Wound Healing

Endothelin (ET)-1 is known for the most potent vasoconstrictive peptide that is released mainly from endothelial cells. Several studies have reported ET-1 signaling is involved in the process of wound healing or fibrosis as well as vasodilation. However, little is known about the role of ET-1 in the...

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Main Authors: Makino, Katsunari, Jinnin, Masatoshi, Aoi, Jun, Kajihara, Ikko, Makino, Takamitsu, Fukushima, Satoshi, Sakai, Keisuke, Nakayama, Kazuhiko, Emoto, Noriaki, Yanagisawa, Masashi, Ihn, Hironobu
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031171/
https://ncbi.nlm.nih.gov/pubmed/24853267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097972
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