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Advances in Understanding the Complex Mechanisms of DNA Interstrand Cross-Link Repair

DNA interstrand cross-links (ICLs) are lesions caused by a variety of endogenous metabolites, environmental exposures, and cancer chemotherapeutic agents that have two reactive groups. The common feature of these diverse lesions is that two nucleotides on opposite strands are covalently joined. ICLs...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Clauson, Cheryl, Schärer, Orlando D., Niedernhofer, Laura
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123742/
https://ncbi.nlm.nih.gov/pubmed/24086043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a012732
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