Dapper1 promotes autophagy by enhancing the Beclin1-Vps34-Atg14L complex formation

Autophagy is an intracellular degradation process to clear up aggregated proteins or aged and damaged organelles. The Beclin1-Vps34-Atg14L complex is essential for autophagosome formation. However, how the complex formation is regulated is unclear. Here, we show that Dapper1 (Dpr1) acts as a critica...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ma, Benyu, Cao, Weipeng, Li, Wenxia, Gao, Chan, Qi, Zhen, Zhao, Yan, Du, Jun, Xue, Hua, Peng, Junya, Wen, Jun, Chen, Hua, Ning, Yuanheng, Huang, Lei, Zhang, Hong, Gao, Xiang, Yu, Li, Chen, Ye-Guang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2014
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123296/
https://ncbi.nlm.nih.gov/pubmed/24980960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.84
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak