Autophagy and mitochondrial alterations in human retinal pigment epithelial cells induced by ethanol: implications of 4-hydroxy-nonenal

Retinal pigment epithelium has a crucial role in the physiology and pathophysiology of the retina due to its location and metabolism. Oxidative damage has been demonstrated as a pathogenic mechanism in several retinal diseases, and reactive oxygen species are certainly important by-products of ethan...

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Hlavní autoři: Flores-Bellver, M, Bonet-Ponce, L, Barcia, J M, Garcia-Verdugo, J M, Martinez-Gil, N, Saez-Atienzar, S, Sancho-Pelluz, J, Jordan, J, Galindo, M F, Romero, F J
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123082/
https://ncbi.nlm.nih.gov/pubmed/25032851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.288
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