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Ethanol-Induced Oxidative Stress Modifies Inflammation and Angiogenesis Biomarkers in Retinal Pigment Epithelial Cells (ARPE-19): Role of CYP2E1 and its Inhibition by Antioxidants

The retinal pigment epithelium (RPE) plays a key role in retinal health, being essential for the protection against reactive oxygen species (ROS). Nevertheless, excessive oxidative stress can induce RPE dysfunction, promoting visual loss. Our aim is to clarify the possible implication of CYP2E1 in e...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Martinez-Gil, Natalia, Vidal-Gil, Lorena, Flores-Bellver, Miguel, Maisto, Rosa, Sancho-Pelluz, Javier, Diaz-Llopis, Manuel, M. Barcia, Jorge, Romero, Francisco J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555214/
https://ncbi.nlm.nih.gov/pubmed/32825644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9090776
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