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CXCR4 and CXCR7 transduce through mTOR in human renal cancer cells

Treatment of metastatic renal cell carcinoma (mRCC) has improved significantly with the advent of agents targeting the mTOR pathway, such as temsirolimus and everolimus. However, their efficacy is thought to be limited by feedback loops and crosstalk with other pathways leading to the development of...

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Detalhes bibliográficos
Main Authors: Ieranò, C, Santagata, S, Napolitano, M, Guardia, F, Grimaldi, A, Antignani, E, Botti, G, Consales, C, Riccio, A, Nanayakkara, M, Barone, M V, Caraglia, M, Scala, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123065/
https://ncbi.nlm.nih.gov/pubmed/24991762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.269
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