CXCR4 and CXCR7 transduce through mTOR in human renal cancer cells

Treatment of metastatic renal cell carcinoma (mRCC) has improved significantly with the advent of agents targeting the mTOR pathway, such as temsirolimus and everolimus. However, their efficacy is thought to be limited by feedback loops and crosstalk with other pathways leading to the development of...

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Bibliografiska uppgifter
Huvudupphovsmän: Ieranò, C, Santagata, S, Napolitano, M, Guardia, F, Grimaldi, A, Antignani, E, Botti, G, Consales, C, Riccio, A, Nanayakkara, M, Barone, M V, Caraglia, M, Scala, S
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2014
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123065/
https://ncbi.nlm.nih.gov/pubmed/24991762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.269
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