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Chemo-Enzymatic Synthesis of Ester-Linked 2-Phenylindole-3-Carboxaldehyde-Monosaccharide Conjugate as Potential Prodrug

Chemo-enzymatic synthesis of ester-linked 2-phenylindole-3-carboxaldehyde-glucose conjugate (2-phenylindole-3-carboxyl-10″-O-β-D-glucosyl ester) was achieved by using plant cell cultures as biocatalysts. The anticancer agent, 2-phenylindole-3-carboxaldehyde, induced apoptosis in cells, whereas 2-phe...

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書誌詳細
主要な著者: Shimoda, Kei, Hamada, Manabu, Yokoi, Hiroshi, Hamada, Hiroki
フォーマット: Artigo
言語:Inglês
出版事項: Libertas Academica 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122544/
https://ncbi.nlm.nih.gov/pubmed/25114553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/BCI.S9961
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