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A Chemo-Enzymatic Synthesis of the (R(P))-Isomer of the Antiviral Prodrug Remdesivir
The Covid-19 pandemic threatens to overwhelm healthcare systems around the world. The only current FDA approved treatment, which directly targets the virus, is the ProTide prodrug remdesivir. In its activated form, remdesivir prevents viral replication by inhibition of the essential RNA-dependent RN...
Tallennettuna:
| Julkaisussa: | Biochemistry |
|---|---|
| Päätekijät: | , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7418565/ https://ncbi.nlm.nih.gov/pubmed/32786401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00591 |
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