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Enzyme-Catalyzed Kinetic Resolution of Chiral Precursors to Antiviral Prodrugs
[Image: see text] Nucleoside analogues are among the most common medications given for the treatment of viral infections and cancers. The therapeutic effectiveness of nucleoside analogues can be dramatically improved by phosphorylation. The ProTide approach was developed using a phosphorylated nucle...
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| Publicado no: | Biochemistry |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2019
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6822272/ https://ncbi.nlm.nih.gov/pubmed/31268686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00530 |
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