A Chemo-Enzymatic Road Map to the Synthesis of CoA Esters

Coenzyme A (CoA) is a ubiquitous cofactor present in every known organism. The thioesters of CoA are core intermediates in many metabolic processes, such as the citric acid cycle, fatty acid biosynthesis and secondary metabolism, including polyketide biosynthesis. Synthesis of CoA-thioesters is vita...

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Bibliografiska uppgifter
Huvudupphovsmän: Dominik M. Peter, Bastian Vögeli, Niña Socorro Cortina, Tobias J. Erb
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI AG 2016-04-01
Serie:Molecules
Ämnen:
CoA-thioester
acylation
acyl-CoA dehydrogenases
enzyme promiscuity
secondary metabolites
polyketide synthase
natural product biosynthesis
biocatalysis
extender units
Länkar:http://www.mdpi.com/1420-3049/21/4/517
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