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An in vitro Blood-brain barrier model combining shear stress and endothelial cell/astrocyte co-culture

BACKGROUND: In vitro blood-brain barrier (BBB) models can be useful for understanding leukocyte-endothelial interactions at this unique vascular-tissue interface. Desirable features of such a model include shear stress, non-transformed cells and co-cultures of brain microvascular endothelial cells w...

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Main Authors: Takeshita, Yukio, Obermeier, Birgit, Cotleur, Anne, Sano, Yasuteru, Kanda, Takashi, Ransohoff, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122330/
https://ncbi.nlm.nih.gov/pubmed/24858797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2014.05.013
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