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Targeted therapies of the LKB1/AMPK pathway for the treatment of insulin resistance

Type 2 diabetes is characterized by elevated serum glucose levels and altered lipid metabolism, due to peripheral insulin resistance and defects of insulin secretion by the pancreatic β-cells. While some cases of obesity and Type 2 diabetes result from genetic dysfunction, the increased worldwide in...

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Hlavní autoři: Yamada, Eijiro, Lee, Ting-Wen A, Pessin, Jeffrey E, Bastie, Claire C
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122297/
https://ncbi.nlm.nih.gov/pubmed/21428801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.10.264
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