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Fyn-dependent regulation of energy expenditure and body weight is mediated by tyrosine phosphorylation of LKB1

Fyn null mice display reduced adiposity associated with increased fatty acid oxidation, energy expenditure and activation of the AMP-dependent protein kinase (AMPK) in skeletal muscle and adipose tissue. The acute pharmacological inhibition of Fyn kinase activity with SU6656 in wild type mice reprod...

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Sonraí Bibleagrafaíochta
Main Authors: Yamada, Eijiro, Pessin, Jeffrey E., Kurland, Irwin J., Schwartz, Gary J., Bastie, Claire C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830006/
https://ncbi.nlm.nih.gov/pubmed/20142099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2009.12.010
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