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Fyn-dependent regulation of energy expenditure and body weight is mediated by tyrosine phosphorylation of LKB1
Fyn null mice display reduced adiposity associated with increased fatty acid oxidation, energy expenditure and activation of the AMP-dependent protein kinase (AMPK) in skeletal muscle and adipose tissue. The acute pharmacological inhibition of Fyn kinase activity with SU6656 in wild type mice reprod...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2830006/ https://ncbi.nlm.nih.gov/pubmed/20142099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2009.12.010 |
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