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Fibronectin Stimulates Endothelin-1 Synthesis in Rat Hepatic Myofibroblasts via a Src/ERK Regulated Signaling Pathway

BACKGROUND AND AIMS: Liver injury serves as an excellent model of wound healing, characterized by increased synthesis of various cytokines and peptides, including the vasoactive peptide endothelin-1. In the liver, wound healing is mediated by effector cells such as hepatic stellate cells, which caus...

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Bibliographic Details
Main Authors: Zhan, Shuxin, Chan, Che-Chang, Serdar, Berrin, Rockey, Don C.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122293/
https://ncbi.nlm.nih.gov/pubmed/19505428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.01.062
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