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Growth inhibitory properties of endothelin-1 in human hepatic myofibroblastic Ito cells. An endothelin B receptor-mediated pathway.

Ito cells play a pivotal role in the development of liver fibrosis associated with chronic liver diseases. During this process, Ito cells acquire myofibroblastic features, proliferate, and synthesize fibrosis components. Considering the reported mitogenic properties of endothelin-1 (ET-1), we invest...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Mallat, A, Fouassier, L, Préaux, A M, Gal, C S, Raufaste, D, Rosenbaum, J, Dhumeaux, D, Jouneaux, C, Mavier, P, Lotersztajn, S
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1995
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185171/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7615814/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118052
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