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Growth inhibitory properties of endothelin-1 in human hepatic myofibroblastic Ito cells. An endothelin B receptor-mediated pathway.

Ito cells play a pivotal role in the development of liver fibrosis associated with chronic liver diseases. During this process, Ito cells acquire myofibroblastic features, proliferate, and synthesize fibrosis components. Considering the reported mitogenic properties of endothelin-1 (ET-1), we invest...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Mallat, A, Fouassier, L, Préaux, A M, Gal, C S, Raufaste, D, Rosenbaum, J, Dhumeaux, D, Jouneaux, C, Mavier, P, Lotersztajn, S
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1995
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185171/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7615814/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118052
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