Growth inhibitory properties of endothelin-1 in human hepatic myofibroblastic Ito cells. An endothelin B receptor-mediated pathway.

Ito cells play a pivotal role in the development of liver fibrosis associated with chronic liver diseases. During this process, Ito cells acquire myofibroblastic features, proliferate, and synthesize fibrosis components. Considering the reported mitogenic properties of endothelin-1 (ET-1), we invest...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Mallat, A, Fouassier, L, Préaux, A M, Gal, C S, Raufaste, D, Rosenbaum, J, Dhumeaux, D, Jouneaux, C, Mavier, P, Lotersztajn, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185171/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7615814/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118052
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