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Endothelin antagonism in experimental hepatic fibrosis. Implications for endothelin in the pathogenesis of wound healing.

The liver's response to chronic injury is fibrosis, which is analogous to wound healing in other organs. Hepatic wounding is characterized by the "activation" of resident stellate cells (lipocytes, Ito cells) to myofibroblast-like cells that produce increased amounts of smooth muscle...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Rockey, D C, Chung, J J
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1996
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507564/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8823303/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118925
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