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Neuronal production of lipocalin-2 as a help-me signal for glial activation

BACKGROUND AND PURPOSE: We explored the hypothesis that injured neurons release lipocalin-2 as a help-me signal. METHODS: In vivo lipocalin-2 responses were assessed in rat focal cerebral ischemia and human stroke brain samples using a combination of ELISA and immunostaining. In vitro, microglia and...

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Detalhes bibliográficos
Main Authors: Xing, Changhong, Wang, Xiaoshu, Cheng, Chongjie, Montaner, Joan, Mandeville, Emiri, Leung, Wendy, van Leyen, Klaus, Lok, Josephine, Wang, Xiaoying, Lo, Eng H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122238/
https://ncbi.nlm.nih.gov/pubmed/24916903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.114.005733
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