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Cerebrovascular degradation of TRKB by MMP9 in the diabetic brain

Diabetes elevates the risk for neurological diseases, but little is known about the underlying mechanisms. Brain-derived neurotrophic factor (BDNF) is secreted by microvascular endothelial cells (ECs) in the brain, functioning as a neuroprotectant through the activation of the neurotrophic tyrosine...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Navaratna, Deepti, Fan, Xiang, Leung, Wendy, Lok, Josephine, Guo, Shuzhen, Xing, Changhong, Wang, Xiaoying, Lo, Eng H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726155/
https://ncbi.nlm.nih.gov/pubmed/23867621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65767
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