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Cerebrovascular degradation of TRKB by MMP9 in the diabetic brain
Diabetes elevates the risk for neurological diseases, but little is known about the underlying mechanisms. Brain-derived neurotrophic factor (BDNF) is secreted by microvascular endothelial cells (ECs) in the brain, functioning as a neuroprotectant through the activation of the neurotrophic tyrosine...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726155/ https://ncbi.nlm.nih.gov/pubmed/23867621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65767 |
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