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Decreased Cerebrovascular Brain-Derived Neurotrophic Factor–Mediated Neuroprotection in the Diabetic Brain

OBJECTIVE: Diabetes is an independent risk factor for stroke. However, the underlying mechanism of how diabetes confers that this risk is not fully understood. We hypothesize that secretion of neurotrophic factors by the cerebral endothelium, such as brain-derived neurotrophic factor (BDNF), is supp...

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Detalhes bibliográficos
Main Authors: Navaratna, Deepti, Guo, Shu-zhen, Hayakawa, Kazhuhide, Wang, Xiaoying, Gerhardinger, Chiara, Lo, Eng H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114398/
https://ncbi.nlm.nih.gov/pubmed/21562076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1371
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