Arhgap36-dependent activation of Gli transcription factors

Hedgehog (Hh) pathway activation and Gli-dependent transcription play critical roles in embryonic patterning, tissue homeostasis, and tumorigenesis. By conducting a genome-scale cDNA overexpression screen, we have identified the Rho GAP family member Arhgap36 as a positive regulator of the Hh pathwa...

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Detalhes bibliográficos
Main Authors: Rack, Paul G., Ni, Jun, Payumo, Alexander Y., Nguyen, Vien, Crapster, J. Aaron, Hovestadt, Volker, Kool, Marcel, Jones, David T. W., Mich, John K., Firestone, Ari J., Pfister, Stefan M., Cho, Yoon-Jae, Chen, James K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121843/
https://ncbi.nlm.nih.gov/pubmed/25024229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322362111
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