Stromal response to Hedgehog signaling restrains pancreatic cancer progression

Pancreatic ductal adenocarcinoma (PDA) is the most lethal of common human malignancies, with no truly effective therapies for advanced disease. Preclinical studies have suggested a therapeutic benefit of targeting the Hedgehog (Hh) signaling pathway, which is activated throughout the course of PDA p...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Lee, John J., Perera, Rushika M., Wang, Huaijun, Wu, Dai-Chen, Liu, X. Shawn, Han, Shiwei, Fitamant, Julien, Jones, Phillip D., Ghanta, Krishna S., Kawano, Sally, Nagle, Julia M., Deshpande, Vikram, Boucher, Yves, Kato, Tomoyo, Chen, James K., Willmann, Jürgen K., Bardeesy, Nabeel, Beachy, Philip A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
Schlagworte:
PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121834/
https://ncbi.nlm.nih.gov/pubmed/25024225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411679111
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge